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ENZYME

ENZYME entry: EC 1.14.20.16

PURL: https://purl.expasy.org/enzyme/EC/1.14.20.16
Accepted Name
4alpha,5beta-5,20-epoxytax-11-ene-4,9-diol 9-dehydrogenase
Alternative Name(s)
T9alpha oxidase
Reaction catalysed
4alpha,5beta-5,20-epoxytax-11-ene-4,9-diol + 2-oxoglutarate + O2 = 4alpha-hydroxy-5beta-5,20-epoxytax-11-en-9-one + succinate + CO2 + H2O
Comment(s)
The enzyme is active in the biosynthetic pathway of paclitaxel (Taxol) in Taxus species (yew).
Cross-references
BRENDA1.14.20.16
EC2PDB1.14.20.16
ExplorEnz1.14.20.16
KEGG Ligand Database for Enzyme Nomenclature1.14.20.16
IUBMB Enzyme Nomenclature1.14.20.16
MEDLINEFind literature relating to 1.14.20.16
MetaCyc1.14.20.16
Rhea expert-curated reactions1.14.20.16

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.20.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-