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ENZYME

ENZYME entry: EC 1.14.20.9

Accepted Name
tyrosine isonitrile desaturase
Reaction catalysed
(2S)-3-(4-hydroxyphenyl)-2-isocyanopropanoate + 2-oxoglutarate + O2 = (2E)-3-(4-hydroxyphenyl)-2-isocyanoprop-2-enoate + CO2 + H2O + succinate
Comment(s)
  • The enzyme is a member of the Fe(2+), 2-oxoglutarate-dependent oxygenases and requires Fe(2+).
  • It has been characterized from bacteria that form the isonitrile- functionalized compound paerucumarin. cf. EC 1.14.20.10.
Cross-references
BRENDA1.14.20.9
EC2PDB1.14.20.9
ExplorEnz1.14.20.9
PRIAM enzyme-specific profiles1.14.20.9
KEGG Ligand Database for Enzyme Nomenclature1.14.20.9
IUBMB Enzyme Nomenclature1.14.20.9
IntEnz1.14.20.9
MEDLINEFind literature relating to 1.14.20.9
MetaCyc1.14.20.9
Rhea expert-curated reactions1.14.20.9
UniProtKB/Swiss-Prot
D4I2N1, PVCB_ERWACQ9I1L4, PVCB_PSEAE

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