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ENZYME

ENZYME entry: EC 1.14.99.1

Accepted Name
prostaglandin-endoperoxide synthase
Alternative Name(s)
PG synthetase
prostaglandin G/H synthase
prostaglandin synthase
prostaglandin synthetase
Reaction catalysed
(5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + 2 O2 = A + H2O + prostaglandin H2
Comment(s)
Acts both as a dioxygenase and as a peroxidase.
Cross-references
BRENDA1.14.99.1
EC2PDB1.14.99.1
ExplorEnz1.14.99.1
PRIAM enzyme-specific profiles1.14.99.1
KEGG Ligand Database for Enzyme Nomenclature1.14.99.1
IUBMB Enzyme Nomenclature1.14.99.1
IntEnz1.14.99.1
MEDLINEFind literature relating to 1.14.99.1
MetaCyc1.14.99.1
Rhea expert-curated reactions1.14.99.1
UniProtKB/Swiss-Prot
O62664, PGH1_BOVINQ8HZR1, PGH1_CANLFP23219, PGH1_HUMAN
P22437, PGH1_MOUSEO97554, PGH1_RABITQ63921, PGH1_RAT
P05979, PGH1_SHEEPO62698, PGH2_BOVINP70682, PGH2_CAVPO
P27607, PGH2_CHICKO19183, PGH2_HORSEP35354, PGH2_HUMAN
Q05769, PGH2_MOUSEO62725, PGH2_NEOVIO02768, PGH2_RABIT
P35355, PGH2_RATP79208, PGH2_SHEEP

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