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ENZYME

ENZYME entry: EC 1.14.99.29

PURL: https://purl.expasy.org/enzyme/EC/1.14.99.29
Accepted Name
deoxyhypusine monooxygenase
Alternative Name(s)
deoxyhypusine dioxygenase
deoxyhypusine hydroxylase
DOHH
Reaction catalysed
[eIF5A protein]-deoxyhypusine + AH2 + O2 = [eIF5A protein]-hypusine + A + H2O
Comment(s)
Catalyzes the final step in the formation of the amino acid hypusine in eukaryotic initiation factor 5A (eIF-5A) (formerly eIF-4D).
Cross-references
BRENDA1.14.99.29
EC2PDB1.14.99.29
ExplorEnz1.14.99.29
KEGG Ligand Database for Enzyme Nomenclature1.14.99.29
IUBMB Enzyme Nomenclature1.14.99.29
MEDLINEFind literature relating to 1.14.99.29
MetaCyc1.14.99.29
Rhea expert-curated reactions1.14.99.29
UniProtKB/Swiss-Prot
Q2QXB3, DOHH1_ORYSJQ2QLW3, DOHH2_ORYSJQ94JW0, DOHH_ARATH
A1CED0, DOHH_ASPCLQ4WHG5, DOHH_ASPFUA2QXL3, DOHH_ASPNC
Q2UMQ8, DOHH_ASPORQ0VC53, DOHH_BOVINQ17949, DOHH_CAEEL
Q59Z14, DOHH_CANALQ6FUV3, DOHH_CANGAQ2H0C0, DOHH_CHAGB
Q5ZIP3, DOHH_CHICKQ1E9L2, DOHH_COCIMP0CN11, DOHH_CRYNB
P0CN10, DOHH_CRYNJQ7ZUX6, DOHH_DANREQ6BKA6, DOHH_DEBHA
Q556G4, DOHH_DICDIQ9V9U4, DOHH_DROMEQ297S2, DOHH_DROPS
Q5AW32, DOHH_EMENIQ8SV71, DOHH_ENCCUQ752Z8, DOHH_EREGS
Q4HZ35, DOHH_GIBZEQ9BU89, DOHH_HUMANQ6CV81, DOHH_KLULA
D9IFD5, DOHH_LEIDOQ96WP5, DOHH_LENEDQ99LN9, DOHH_MOUSE
Q4PHU4, DOHH_MYCMDA1DFW7, DOHH_NEOFIQ7S891, DOHH_NEUCR
Q0UHL8, DOHH_PHANOA5JZ19, DOHH_PLAVSQ5PPJ4, DOHH_RAT
Q9P6K9, DOHH_SCHPOQ66KT3, DOHH_XENLAQ6CHJ7, DOHH_YARLI
P47120, DOHH_YEAST

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