ENZYME entry: EC 1.14.99.53
| Accepted Name |
|---|
| Lytic chitin monooxygenase.
|
| Alternative Name(s) |
|---|
| Chitin oxidohydrolase. |
| LPMO. |
| Reaction catalysed |
|---|
| ((1->4)-N-acetyl-beta-D-glucosaminyl)(n+m) + reduced acceptor + O(2) <=> ((1->4)-N-acetyl-beta-D-glucosaminyl)(m-1)-(1->4)-2-(acetylamino)-2-deoxy-D-glucono-1,5-lactone + ((1->4)-N-acetyl-beta-D-glucosaminyl)(n) + acceptor + H(2)O |
| Cofactor(s) |
|---|
| Cu(2+).
|
| Comment(s) |
|---|
- The enzyme cleaves chitin in an oxidative manner, releasing fragments
of chitin with an N-acetylamino-D-glucono-1,5-lactone at the reducing
end.
- The initially formed lactone at the reducing end of the shortend
chitin chain quickly hydrolyzes spontaneously to the aldonic acid.
- In vitro ascorbate can serve as reducing agent.
|
| Cross-references |
|---|
| BRENDA | 1.14.99.53 |
| EC2PDB | 1.14.99.53 |
| ExplorEnz | 1.14.99.53 |
| PRIAM enzyme-specific profiles | 1.14.99.53 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.99.53 |
| IUBMB Enzyme Nomenclature | 1.14.99.53 |
| IntEnz | 1.14.99.53 |
| MEDLINE | Find literature relating to 1.14.99.53 |
| MetaCyc | 1.14.99.53 |
| UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.14.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.14.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-