ENZYME entry: EC 1.14.99.53
Accepted Name |
Lytic chitin monooxygenase.
|
Alternative Name(s) |
Chitin oxidohydrolase. |
LPMO. |
Reaction catalysed |
((1->4)-N-acetyl-beta-D-glucosaminyl)(n+m) + reduced acceptor + O(2) <=> ((1->4)-N-acetyl-beta-D-glucosaminyl)(m-1)-(1->4)-2-(acetylamino)-2-deoxy-D-glucono-1,5-lactone + ((1->4)-N-acetyl-beta-D-glucosaminyl)(n) + acceptor + H(2)O |
Cofactor(s) |
Cu(2+).
|
Comment(s) |
- The enzyme cleaves chitin in an oxidative manner, releasing fragments
of chitin with an N-acetylamino-D-glucono-1,5-lactone at the reducing
end.
- The initially formed lactone at the reducing end of the shortend
chitin chain quickly hydrolyzes spontaneously to the aldonic acid.
- In vitro ascorbate can serve as reducing agent.
|
Cross-references |
BRENDA | 1.14.99.53 |
EC2PDB | 1.14.99.53 |
ExplorEnz | 1.14.99.53 |
PRIAM enzyme-specific profiles | 1.14.99.53 |
KEGG Ligand Database for Enzyme Nomenclature | 1.14.99.53 |
IUBMB Enzyme Nomenclature | 1.14.99.53 |
IntEnz | 1.14.99.53 |
MEDLINE | Find literature relating to 1.14.99.53 |
MetaCyc | 1.14.99.53 |
Rhea expert-curated reactions | 1.14.99.53 |
UniProtKB/Swiss-Prot |
|
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