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ENZYME entry: EC 1.14.99.59

Accepted Name
Tryptamine 4-monooxygenase.
Reaction catalysed
Tryptamine + reduced acceptor + O(2) <=> 4-hydroxytryptamine + acceptor + H(2)O
Cofactor(s)
Heme-thiolate.
Comment(s)
  • Isolated from the fungus Psilocybe cubensis.
  • Involved in the biosynthesis of the psychoactive compound psilocybin.
Cross-references
BRENDA1.14.99.59
EC2PDB1.14.99.59
ExplorEnz1.14.99.59
PRIAM enzyme-specific profiles1.14.99.59
KEGG Ligand Database for Enzyme Nomenclature1.14.99.59
IUBMB Enzyme Nomenclature1.14.99.59
IntEnz1.14.99.59
MEDLINEFind literature relating to 1.14.99.59
MetaCyc1.14.99.59
UniProtKB/Swiss-Prot
P0DPA7, PSIH_PSICU;  A0A286LF02, PSIH_PSICY;  

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