ID 1.14.99.68 DE 4-aminobenzoate N-oxygenase. CA 4-aminobenzoate + AH2 + 2 O2 = 4-nitrobenzoate + A + 2 H2O. CC -!- The enzyme, characterized from the bacterium Streptomyces thioluteus, CC catalyzes an early step in the biosynthesis of the antibiotic CC aureothin. CC -!- It contains a carboxylate-bridged binuclear non-heme iron cluster. CC -!- The native electron donor has not been identified, but is likely an CC iron-sulfur protein. CC -!- The reaction mechanism involves formation of an extremely stable CC peroxo intermediate that catalyzes three two-electron oxidations via CC a hydroxylamine and dihydroxylamine intermediates. cf. EC 1.14.99.67. DR Q70KH9, AURF_STRTU ; //