ID 1.16.3.3 DE manganese oxidase. CA 2 Mn(2+) + O2 + 2 H2O = 2 MnO2 + 4 H(+). CC -!- The enzyme, which belongs to the multicopper oxidase family, is found CC in many bacterial strains. CC -!- It oxidizes soluble Mn(II) to insoluble manganese oxides. CC -!- Since the enzyme is localized to the outer surface of the cell, CC its activity usually results in encrustation of the cells by the CC oxides. CC -!- The physiological function of bacterial Mn(II) oxidation remains CC unclear. //