ENZYME entry: EC 1.17.1.1
| Accepted Name |
|---|
| CDP-4-dehydro-6-deoxyglucose reductase.
|
| Alternative Name(s) |
|---|
| CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system. |
| CDP-4-keto-6-deoxyglucose reductase. |
| CDP-4-keto-deoxy-glucose reductase. |
| cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase. |
| cytidine diphospho-4-keto-6-deoxy-D-glucose reductase. |
| NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase. |
| Reaction catalysed |
|---|
- CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NAD(+) <=> CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH
- CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NADP(+) <=> CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH
|
| Comment(s) |
|---|
- The enzyme consists of two proteins.
- One forms an enzyme-bound adduct of the CDP-4-dehydro-6-deoxyglucose
with pyridoxamine phosphate, in which the 3-hydroxy group has been
removed.
- The second catalyzes the reduction of this adduct by NAD(P)H and
release of the CDP-4-dehydro-3,6-dideoxy-D-glucose and pyridoxamine
phosphate.
|
| Cross-references |
|---|
| BRENDA | 1.17.1.1 |
| EC2PDB | 1.17.1.1 |
| ExplorEnz | 1.17.1.1 |
| PRIAM enzyme-specific profiles | 1.17.1.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.17.1.1 |
| IUBMB Enzyme Nomenclature | 1.17.1.1 |
| IntEnz | 1.17.1.1 |
| MEDLINE | Find literature relating to 1.17.1.1 |
| MetaCyc | 1.17.1.1 |
| Rhea expert-curated reactions | 1.17.1.1 |
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