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ENZYME entry: EC

Accepted Name
CDP-4-dehydro-6-deoxyglucose reductase.
Alternative Name(s)
CDP-4-keto-6-deoxy-D-glucose-3-dehydrogenase system.
CDP-4-keto-6-deoxyglucose reductase.
CDP-4-keto-deoxy-glucose reductase.
cytidine diphosphate 4-keto-6-deoxy-D-glucose-3-dehydrogenase.
cytidine diphospho-4-keto-6-deoxy-D-glucose reductase.
NAD(P)H:CDP-4-keto-6-deoxy-D-glucose oxidoreductase.
Reaction catalysed
  • CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NAD(+) <=> CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADH
  • CDP-4-dehydro-3,6-dideoxy-alpha-D-glucose + H2O + NADP(+) <=> CDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH
  • The enzyme consists of two proteins.
  • One forms an enzyme-bound adduct of the CDP-4-dehydro-6-deoxyglucose with pyridoxamine phosphate, in which the 3-hydroxy group has been removed.
  • The second catalyzes the reduction of this adduct by NAD(P)H and release of the CDP-4-dehydro-3,6-dideoxy-D-glucose and pyridoxamine phosphate.
PRIAM enzyme-specific profiles1.17.1.1
KEGG Ligand Database for Enzyme Nomenclature1.17.1.1
IUBMB Enzyme Nomenclature1.17.1.1
MEDLINEFind literature relating to
Rhea expert-curated reactions1.17.1.1

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