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ENZYME

ENZYME entry: EC 1.17.2.1

PURL: https://purl.expasy.org/enzyme/EC/1.17.2.1
Accepted Name
nicotinate dehydrogenase (cytochrome)
Alternative Name(s)
nicotinate hydroxylase
nicotinic acid hydroxylase
Reaction catalysed
2 Fe(III)-[cytochrome] + nicotinate + H2O = 2 Fe(II)-[cytochrome] + 6-hydroxynicotinate + 2 H(+)
Comment(s)
  • This two-component enzyme from Pseudomonas belongs to the family of xanthine dehydrogenases, but differs from most other members of this family.
  • While most members contain an FAD cofactor, the large subunit of this enzyme contains three c-type cytochromes, enabling it to interact with the electron transfer chain, probably by delivering the electrons to a cytochrome oxidase.
Cross-references
BRENDA1.17.2.1
EC2PDB1.17.2.1
ExplorEnz1.17.2.1
KEGG Ligand Database for Enzyme Nomenclature1.17.2.1
IUBMB Enzyme Nomenclature1.17.2.1
MEDLINEFind literature relating to 1.17.2.1
MetaCyc1.17.2.1
Rhea expert-curated reactions1.17.2.1
UniProtKB/Swiss-Prot
Q88FX9, NICA_PSEPKQ88FX8, NICB_PSEPK

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