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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.17.3.3

Accepted Name
6-hydroxynicotinate dehydrogenase.
Alternative Name(s)
6-hydroxynicotinate hydroxylase.
6-hydroxynicotinic acid dehydrogenase.
6-hydroxynicotinic acid hydroxylase.
Reaction catalysed
6-hydroxynicotinate + H(2)O + O(2) <=> 2,6-dihydroxynicotinate + H(2)O(2)
Cofactor(s)
FAD; Iron-sulfur; Mo-molybdopterin.
Comment(s)
  • The enzyme also has a catalytically essential, labile selenium that can be removed by reaction with cyanide.
  • In Bacillus niacini, this enzyme is required for growth on nicotinic acid.
Cross-references
BRENDA1.17.3.3
EC2PDB1.17.3.3
ExplorEnz1.17.3.3
PRIAM enzyme-specific profiles1.17.3.3
KEGG Ligand Database for Enzyme Nomenclature1.17.3.3
IUBMB Enzyme Nomenclature1.17.3.3
IntEnz1.17.3.3
MEDLINEFind literature relating to 1.17.3.3
MetaCyc1.17.3.3

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-