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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.17.3.4

Accepted Name
Juglone 3-hydroxylase.
Alternative Name(s)
Naphthoquinone hydroxylase.
Reaction catalysed
2 juglone + O(2) <=> 2 3,5-dihydroxy-1,4-naphthoquinone
Comment(s)
  • Even though oxygen is consumed, molecular oxygen is not incorporated into the product.
  • Catalysis starts by incorporation of an oxygen atom from a water molecule into the substrate.
  • The naphthalene-1,2,4,8-tetrol intermediate is then oxidized by molecular oxygen, which is reduced to water.
  • Also acts on 1,4-naphthoquinone, naphthazarin and 2-chloro-1,4- naphthoquinone.
  • Formerly EC 1.14.99.27.
Cross-references
BRENDA1.17.3.4
EC2PDB1.17.3.4
ExplorEnz1.17.3.4
PRIAM enzyme-specific profiles1.17.3.4
KEGG Ligand Database for Enzyme Nomenclature1.17.3.4
IUBMB Enzyme Nomenclature1.17.3.4
IntEnz1.17.3.4
MEDLINEFind literature relating to 1.17.3.4
MetaCyc1.17.3.4

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-