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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.17.99.2

Accepted Name
Ethylbenzene hydroxylase.
Alternative Name(s)
Ethylbenzene dehydrogenase.
Reaction catalysed
Ethylbenzene + H(2)O + acceptor <=> (S)-1-phenylethanol + reduced acceptor
Cofactor(s)
Heme; Iron-sulfur; Mo-molybdopterin.
Comment(s)
  • Involved in the anaerobic catabolism of ethylbenzene by denitrifying bacteria.
  • Ethylbenzene is the preferred substrate; the enzyme from some strains oxidizes propylbenzene, 1-ethyl-4-fluorobenzene, 3-methylpent-2-ene and ethylidenecyclohexane.
  • Toluene is not oxidized.
  • p-benzoquinone or ferrocenium can act as electron acceptor.
Cross-references
BRENDA1.17.99.2
EC2PDB1.17.99.2
ExplorEnz1.17.99.2
PRIAM enzyme-specific profiles1.17.99.2
KEGG Ligand Database for Enzyme Nomenclature1.17.99.2
IUBMB Enzyme Nomenclature1.17.99.2
IntEnz1.17.99.2
MEDLINEFind literature relating to 1.17.99.2
MetaCyc1.17.99.2

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.17.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-