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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.17.99.7

Accepted Name
Formate dehydrogenase (acceptor).
Alternative Name(s)
Formate dehydrogenase H.
Formate dehydrogenase O.
Reaction catalysed
Formate + acceptor <=> CO(2) + reduced acceptor
Comment(s)
  • Formate dehydrogenase H is a cytoplasmic enzyme that oxidizes formate without oxygen transfer, transferring electrons to a hydrogenase.
  • The two enzymes form the formate-hydrogen lyase complex.
  • The enzyme contains a selenocysteine residue.
  • Formerly EC 1.1.99.33.
Cross-references
PROSITEPDOC00392
BRENDA1.17.99.7
EC2PDB1.17.99.7
ExplorEnz1.17.99.7
PRIAM enzyme-specific profiles1.17.99.7
KEGG Ligand Database for Enzyme Nomenclature1.17.99.7
IUBMB Enzyme Nomenclature1.17.99.7
IntEnz1.17.99.7
MEDLINEFind literature relating to 1.17.99.7
MetaCyc1.17.99.7
UniProtKB/Swiss-Prot
P07658, FDHF_ECOLI

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