Expasy logo

ENZYME

ENZYME entry: EC 1.2.1.12

Accepted Name
glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
Alternative Name(s)
GAPDH
NAD-dependent glyceraldehyde-3-phosphate dehydrogenase
triosephosphate dehydrogenase
Reaction catalysed
D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH
Comment(s)
Also acts very slowly on D-glyceraldehyde and some other aldehydes; thiols can replace phosphate.
Cross-references
BRENDA1.2.1.12
EC2PDB1.2.1.12
ExplorEnz1.2.1.12
PRIAM enzyme-specific profiles1.2.1.12
KEGG Ligand Database for Enzyme Nomenclature1.2.1.12
IUBMB Enzyme Nomenclature1.2.1.12
IntEnz1.2.1.12
MEDLINEFind literature relating to 1.2.1.12
MetaCyc1.2.1.12
Rhea expert-curated reactions1.2.1.12
UniProtKB/Swiss-Prot
P32635, G3P1_AGABIQ4MQ58, G3P1_BACCEP09124, G3P1_BACSU
P04970, G3P1_CAEELQ6FPW3, G3P1_CANGAP07486, G3P1_DROME
P0A9B4, G3P1_ECO57P0A9B2, G3P1_ECOLIP53429, G3P1_GIAIN
O16027, G3P1_GLOROP17819, G3P1_KLULAP84998, G3P1_KLUMA
Q9C136, G3P1_MUCCLP80506, G3P1_NOSS1P78958, G3P1_SCHPO
Q5HHP5, G3P1_STAACP0A036, G3P1_STAAMP99136, G3P1_STAAN
Q6GIL8, G3P1_STAARQ6GB58, G3P1_STAASP0A037, G3P1_STAAW
Q5HQV4, G3P1_STAEQQ8CPY5, G3P1_STAESP54226, G3P1_STRAE
Q82IZ2, G3P1_STRAWP49433, G3P1_SYNY3P17729, G3P1_TRIKO
P34916, G3P1_TRIV2P00360, G3P1_YEASTP32636, G3P2_AGABI
P83077, G3P2_BACCEP32809, G3P2_CAEBRP17329, G3P2_CAEEL
Q6FSM4, G3P2_CANGAQ5MJ86, G3P2_DANREP07487, G3P2_DROME
O44104, G3P2_DROPSO44105, G3P2_DROSUP58072, G3P2_ECO57
Q6CX23, G3P2_KLULAQ01077, G3P2_KLUMAQ96UF2, G3P2_MUCCL
O43026, G3P2_SCHPOQ5HF86, G3P2_STAACP64180, G3P2_STAAM
P99067, G3P2_STAANQ6GG19, G3P2_STAARQ6G8N9, G3P2_STAAS
P64181, G3P2_STAAWQ5HNL7, G3P2_STAEQQ8CNY0, G3P2_STAES
E3VWI2, G3P2_STRAEQ829W3, G3P2_STRAWP17730, G3P2_TRIKO
P00358, G3P2_YEASTP32810, G3P3_CAEBRP17330, G3P3_CAEEL
P84999, G3P3_KLUMAQ96UF1, G3P3_MUCCLP58559, G3P3_NOSS1
P34918, G3P3_TRIV2P00359, G3P3_YEASTP17331, G3P4_CAEEL
P25858, G3PC1_ARATHP26517, G3PC1_HORVUP08735, G3PC1_MAIZE
Q0J8A4, G3PC1_ORYSJQ9FX54, G3PC2_ARATHP08477, G3PC2_HORVU
Q09054, G3PC2_MAIZEQ7FAH2, G3PC2_ORYSJQ43247, G3PC3_MAIZE
Q6K5G8, G3PC3_ORYSJP25861, G3PC_ANTMAP49644, G3PC_CHLRE
P34920, G3PC_CHOCRQ42671, G3PC_CRAPLP50321, G3PC_CUPNH
P34921, G3PC_DIACAQ39769, G3PC_GINBIP54270, G3PC_GRAGA
Q01558, G3PC_LEIMEP26518, G3PC_MAGLIP17878, G3PC_MESCR
A2YQT7, G3PC_ORYSIP34922, G3PC_PEAP26519, G3PC_PETCR
P26520, G3PC_PETHYP34923, G3PC_PHYPAP34924, G3PC_PINSY
P85954, G3PC_PSEMZP26521, G3PC_RANACQ8VXQ8, G3PC_SCEVA
P04796, G3PC_SINALQ41595, G3PC_TAXBAP09094, G3PC_TOBAC
P10097, G3PC_TRYBBO96423, G3PG_CRIFAQ27890, G3PG_LEIME
P22512, G3PG_TRYBBP22513, G3PG_TRYCRQ9SAJ6, G3PP1_ARATH
Q5E924, G3PP2_ARATHP50322, G3PP_CUPNHQ2KJE5, G3PT_BOVIN
O14556, G3PT_HUMANQ4R3T1, G3PT_MACFAP86211, G3PT_MESAU
Q64467, G3PT_MOUSEQ9ESV6, G3PT_RATQ9HFX1, G3P_AJECA
P55071, G3P_AMAMUO67161, G3P_AQUAEQ12552, G3P_ASPNG
Q9HGY7, G3P_ASPORP24750, G3P_ATLHEP34783, G3P_ATRNU
Q59199, G3P_BACFRQ00640, G3P_BLUHOQ00301, G3P_BOLED
P46795, G3P_BORBUP46796, G3P_BORHEP10096, G3P_BOVIN
P48812, G3P_BRUMAP57384, G3P_BUCAIQ07234, G3P_BUCAP
Q89AK1, G3P_BUCBPQ92211, G3P_CANAWQ28259, G3P_CANLF
P70685, G3P_CAVPOP29272, G3P_CERSPC0HLQ6, G3P_CHAMQ
P00356, G3P_CHICKQ9PJN6, G3P_CHLMUQ9Z7T0, G3P_CHLPN
B0B879, G3P_CHLT2P0CE13, G3P_CHLTRP24748, G3P_CITFR
Q00584, G3P_CLAP2O52631, G3P_CLOABQ59309, G3P_CLOPA
P29497, G3P_COCHEQ1DTF9, G3P_COCIMP28844, G3P_COCLU
Q8J1H3, G3P_COCP7P35143, G3P_COLGLO57479, G3P_COLLI
P54117, G3P_COLLNQ01651, G3P_CORGLQ05025, G3P_COTJA
P17244, G3P_CRIGRP0CN75, G3P_CRYNBP0CN74, G3P_CRYNJ
P19089, G3P_CRYPAQ9Y796, G3P_CUTCUQ5XJ10, G3P_DANRE
Q6BMK0, G3P_DEBHAQ94469, G3P_DICDIQ01597, G3P_DROHY
Q27652, G3P_ECHMUP0A9B3, G3P_ECOL6P20445, G3P_EMENI
Q757I2, G3P_EREGSB7LQ20, G3P_ESCF3P0C8Z1, G3P_ESCFE
Q9N2D5, G3P_FELCAP00362, G3P_GEOSEQ4U3L0, G3P_GLOMM
P44304, G3P_HAEINQ9ZKT0, G3P_HELPJP55971, G3P_HELPY
P15115, G3P_HEYCOP00357, G3P_HOMAMP04406, G3P_HUMAN
P87197, G3P_HYPATP80534, G3P_JACORQ59800, G3P_KITAU
P24163, G3P_KLEAEP24164, G3P_KLEPNO32755, G3P_LACDE
P55070, G3P_LACDTP52987, G3P_LACLAQ9UR38, G3P_LENED
Q92243, G3P_LYOSHQ9N655, G3P_MASBAO57672, G3P_MELGA
P51640, G3P_MESAUP53430, G3P_MONPUP16858, G3P_MOUSE
A3FKF7, G3P_MUSPFP94915, G3P_MYCAVP64179, G3P_MYCBO
A0A0H3MAB5, G3P_MYCBPP47543, G3P_MYCGEP46713, G3P_MYCLE
P75358, G3P_MYCPNA0QWW2, G3P_MYCS2P9WN82, G3P_MYCTO
P9WN83, G3P_MYCTUP83601, G3P_NAEFOP54118, G3P_NEUCR
O59841, G3P_OGAPDQ8TFJ2, G3P_OMPOLO42259, G3P_ONCMY
O01360, G3P_ONCVOP56649, G3P_PANVRQ8X1X3, G3P_PARBA
Q5R2J2, G3P_PELSIQ01982, G3P_PHACHQ9P8C0, G3P_PHANO
O13507, G3P_PHARHP26988, G3P_PHYINQ92263, G3P_PICPA
P00355, G3P_PIGQ9UW96, G3P_PLESAP32637, G3P_PODAS
Q5RAB4, G3P_PONABP23722, G3P_PRIM3P27726, G3P_PSEAE
P24751, G3P_PSEVUP46406, G3P_RABITP52694, G3P_RALN1
P04797, G3P_RATQ8NK47, G3P_RHIMIP0A1P1, G3P_SALTI
P0A1P0, G3P_SALTYP32638, G3P_SCHCOP20287, G3P_SCHMA
Q96US8, G3P_SCLSCP24166, G3P_SERMAP24753, G3P_SEROD
Q28554, G3P_SHEEPI2BA89, G3P_SHIBCP0DJO7, G3P_SHIBL
P0A9B5, G3P_SHIFLQ8WZN0, G3P_SORMAQ4KYY3, G3P_SPECI
P0A038, G3P_STAAUQ9Z518, G3P_STRCOQ59906, G3P_STREQ
P0C0G7, G3P_STRP1P0DB18, G3P_STRP3Q5XDW3, G3P_STRP6
P68777, G3P_STRP8P0DB19, G3P_STRPQP0C0G6, G3P_STRPY
P00361, G3P_THEAQP17721, G3P_THEMAO83816, G3P_TREPA
P09317, G3P_USTMAQ9UVC0, G3P_WICCFP51009, G3P_XANFL
P51469, G3P_XENLAQ6CCU7, G3P_YARLIP08439, G3P_ZYGRO
P09316, G3P_ZYMMOQ2U0J7, HEPG_ASPOR

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-