Home  |  Contact

ENZYME entry: EC 1.2.1.19

Accepted Name
Aminobutyraldehyde dehydrogenase.
Alternative Name(s)
1-pyrroline dehydrogenase.
4-aminobutanal dehydrogenase.
ABALDH.
Gamma-guanidinobutyraldehyde dehydrogenase.
Reaction catalysed
4-aminobutanal + NAD(+) + H(2)O <=> 4-aminobutanoate + NADH
Comment(s)
  • The enzyme from some species exhibits broad substrate specificity and has a marked preference for straight-chain aldehydes (up to 7 carbon atoms) as substrates.
  • The plant enzyme also acts on 4-guanidinobutanal (cf. EC 1.2.1.54).
  • As 1-pyrroline and 4-aminobutanal are in equilibrium and can be interconverted spontaneously, 1-pyrroline may act as the starting substrate.
  • Formerly EC 1.5.1.35.
Cross-references
PROSITEPDOC00068
BRENDA1.2.1.19
EC2PDB1.2.1.19
ExplorEnz1.2.1.19
PRIAM enzyme-specific profiles1.2.1.19
KEGG Ligand Database for Enzyme Nomenclature1.2.1.19
IUBMB Enzyme Nomenclature1.2.1.19
IntEnz1.2.1.19
MEDLINEFind literature relating to 1.2.1.19
MetaCyc1.2.1.19
Rhea expert-curated reactions1.2.1.19
UniProtKB/Swiss-Prot
A0A0E3T552, AADH1_MALDO;  Q8VWZ1, AADH1_PEA;  Q56R04, AADH1_SOLLC;  
C6KEM4, AADH2_MAIZE;  A0A0E3T3B5, AADH2_MALDO;  Q93YB2, AADH2_PEA;  
B6ECN9, AADH2_SOLLC;  A8AGJ9, ABDH_CITK8;  A7ZLN7, ABDH_ECO24;  
B7URJ0, ABDH_ECO27;  B7MMS8, ABDH_ECO45;  B7L6F9, ABDH_ECO55;  
Q8X9W5, ABDH_ECO57;  B5Z0W0, ABDH_ECO5E;  B7MUN0, ABDH_ECO81;  
B7LZ33, ABDH_ECO8A;  C4ZVI3, ABDH_ECOBW;  B1XDF5, ABDH_ECODH;  
A8A002, ABDH_ECOHS;  A1AB46, ABDH_ECOK1;  Q0THX6, ABDH_ECOL5;  
Q8FHK7, ABDH_ECOL6;  B1IS15, ABDH_ECOLC;  P77674, ABDH_ECOLI;  
B7N4K1, ABDH_ECOLU;  B6IAI9, ABDH_ECOSE;  B1LFH3, ABDH_ECOSM;  
Q1RBX3, ABDH_ECOUT;  A4WAR9, ABDH_ENT38;  B7LR95, ABDH_ESCF3;  
Q6D6Y7, ABDH_PECAS;  C6DD82, ABDH_PECCP;  A9MQY3, ABDH_SALAR;  
Q57P61, ABDH_SALCH;  Q5PHV8, ABDH_SALPA;  A9MYQ4, ABDH_SALPB;  
C0Q4N4, ABDH_SALPC;  Q8Z747, ABDH_SALTI;  Q8ZPC9, ABDH_SALTY;  
A8GHZ8, ABDH_SERP5;  Q32FQ5, ABDH_SHIDS;  Q0T431, ABDH_SHIF8;  
Q83R90, ABDH_SHIFL;  Q3Z1H6, ABDH_SHISS;  C0P9J6, ADH1A_MAIZE;  
G5DDC2, ADH1B_MAIZE;  P48644, AL1A1_BOVIN;  P27463, AL1A1_CHICK;  
P15437, AL1A1_HORSE;  P00352, AL1A1_HUMAN;  Q8HYE4, AL1A1_MACFA;  
P86886, AL1A1_MESAU;  P24549, AL1A1_MOUSE;  Q8MI17, AL1A1_RABIT;  
P51647, AL1A1_RAT;  P51977, AL1A1_SHEEP;  P49189, AL9A1_HUMAN;  
Q9JLJ3, AL9A1_RAT;  Q9S795, BADH1_ARATH;  Q9STS1, BADH2_ARATH;  
P17202, BADH_SPIOL;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-