ID 1.2.1.20 DE glutarate-semialdehyde dehydrogenase. CA 5-oxopentanoate + H2O + NADP(+) = glutarate + 2 H(+) + NADPH. CC -!- The enzyme, characterized from multiple Pseudomonas strains, CC participates in L-lysine degradation. CC -!- Unlike earlier claims, it prefers NADP(+) to NAD(+). //