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ENZYME entry: EC 1.2.1.58

Accepted Name
Phenylglyoxylate dehydrogenase (acylating).
Reaction catalysed
Phenylglyoxylate + NAD(+) + CoA <=> benzoyl-S-CoA + CO(2) + NADH
Cofactor(s)
FAD; Iron-sulfur; Thiamine diphosphate.
Comment(s)
  • The enzyme from Azoarcus evansii is specific for phenylglyoxylate.
  • 2-oxoisovalerate is oxidized at 15% of the rate for phenylglyoxylate.
  • Also reduces viologen dyes.
Cross-references
BRENDA1.2.1.58
EC2PDB1.2.1.58
ExplorEnz1.2.1.58
PRIAM enzyme-specific profiles1.2.1.58
KEGG Ligand Database for Enzyme Nomenclature1.2.1.58
IUBMB Enzyme Nomenclature1.2.1.58
IntEnz1.2.1.58
MEDLINEFind literature relating to 1.2.1.58
MetaCyc1.2.1.58
Rhea expert-curated reactions1.2.1.58
UniProtKB/Swiss-Prot
Q8L3B3, PADE_AROEV;  Q8L3B2, PADF_AROEV;  Q8L3B1, PADG_AROEV;  
Q8L3B0, PADH_AROEV;  Q8L3A9, PADI_AROEV;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-