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ENZYME entry: EC 1.2.1.64

Accepted Name
4-hydroxybenzaldehyde dehydrogenase (NAD(+)).
Alternative Name(s)
4-hydroxybenzaldehyde dehydrogenase.
p-hydroxybenzaldehyde dehydrogenase.
Reaction catalysed
4-hydroxybenzaldehyde + NAD(+) + H(2)O <=> 4-hydroxybenzoate + NADH
Comment(s)
  • The bacterial enzyme (characterized from an unidentified denitrifying bacterium) is involved in an anaerobic toluene degradation pathway.
  • The plant enzyme is involved in formation of 4-hydroxybenzoate, a cell wall-bound phenolic acid that plays a major role in plant defense against pathogens.
  • Cf. EC 1.2.1.96.
Cross-references
BRENDA1.2.1.64
EC2PDB1.2.1.64
ExplorEnz1.2.1.64
PRIAM enzyme-specific profiles1.2.1.64
KEGG Ligand Database for Enzyme Nomenclature1.2.1.64
IUBMB Enzyme Nomenclature1.2.1.64
IntEnz1.2.1.64
MEDLINEFind literature relating to 1.2.1.64
MetaCyc1.2.1.64
Rhea expert-curated reactions1.2.1.64
UniProtKB/Swiss-Prot
Q04458, HFD1_YEAST

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