ENZYME

A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.2.1.74

Accepted Name
Abieta-7,13-dien-18-al dehydrogenase.
Alternative Name(s)
Abietadienal dehydrogenase.
Reaction catalysed
Abieta-7,13-diene-18-al + H(2)O + NAD(+) <=> abieta-7,13-diene-18-oate + NADH
Comment(s)
Abietic acid is the principle component of conifer resin. This enzyme catalyzes the last step of the pathway of abietic acid biosynthesis in Abies grandis (grand fir). The activity has been demonstrated in cell-free stem extracts of A.grandis, was present in the cytoplasm, and required NAD(+) as cofactor. The enzyme is expressed constitutively at a high level, and is not inducible by wounding of the plant tissue.
Cross-references
BRENDA	1.2.1.74
EC2PDB	1.2.1.74
ExplorEnz	1.2.1.74
PRIAM enzyme-specific profiles	1.2.1.74
KEGG Ligand Database for Enzyme Nomenclature	1.2.1.74
IUBMB Enzyme Nomenclature	1.2.1.74
IntEnz	1.2.1.74
MEDLINE	Find literature relating to 1.2.1.74
MetaCyc	1.2.1.74

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