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ENZYME

ENZYME entry: EC 1.2.1.79

PURL: https://purl.expasy.org/enzyme/EC/1.2.1.79
Accepted Name
succinate-semialdehyde dehydrogenase (NADP(+))
Reaction catalysed
succinate semialdehyde + NADP(+) + H2O = succinate + NADPH + 2 H(+)
Comment(s)
  • This enzyme participates in the degradation of glutamate and 4-aminobutyrate.
  • It is similar to EC 1.2.1.24 and EC 1.2.1.16 but is specific for NADP(+).
  • The enzyme from Escherichia coli is 20-fold more active with NADP(+) than NAD(+).
Cross-references
BRENDA1.2.1.79
EC2PDB1.2.1.79
ExplorEnz1.2.1.79
KEGG Ligand Database for Enzyme Nomenclature1.2.1.79
IUBMB Enzyme Nomenclature1.2.1.79
MEDLINEFind literature relating to 1.2.1.79
MetaCyc1.2.1.79
Rhea expert-curated reactions1.2.1.79
UniProtKB/Swiss-Prot
A0QMB9, GABD1_MYCA1A1KF54, GABD1_MYCBPO69497, GABD1_MYCLE
Q73TP5, GABD1_MYCPAA5TYV9, GABD1_MYCTAP9WNX8, GABD1_MYCTO
P9WNX9, GABD1_MYCTUA0PN13, GABD1_MYCUAQ7TZP3, GABD2_MYCBO
A1KJE8, GABD2_MYCBPA0R4Q0, GABD2_MYCS2A5U390, GABD2_MYCTA
P9WNX6, GABD2_MYCTOP9WNX7, GABD2_MYCTUA0PST9, GABD2_MYCUA
P94428, GABD_BACSUO32507, GABD_DEIRAP25526, GABD_ECOLI
P55653, GABD_SINFNQ55585, GABD_SYNY3

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-