A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.2.1.84
| Accepted Name |
|---|
| Alcohol-forming fatty acyl-CoA reductase.
|
| Reaction catalysed |
|---|
| A long-chain acyl-CoA + 2 NADPH <=> CoA + a long-chain alcohol + 2 NADP(+) |
| Comment(s) |
|---|
- The enzyme has been characterized from the plant Simmondsia chinensis
(jojoba).
- The alcohol is formed by a four-electron reduction of fatty acyl-CoA.
- Although the reaction proceeds through an aldehyde intermediate,
a free aldehyde is not released.
- The recombinant enzyme was shown to accept saturated and mono-
unsaturated fatty acyl-CoAs of 16 to 22 carbons.
|
| Cross-references |
|---|
| BRENDA | 1.2.1.84 |
| EC2PDB | 1.2.1.84 |
| ExplorEnz | 1.2.1.84 |
| PRIAM enzyme-specific profiles | 1.2.1.84 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.1.84 |
| IUBMB Enzyme Nomenclature | 1.2.1.84 |
| IntEnz | 1.2.1.84 |
| MEDLINE | Find literature relating to 1.2.1.84 |
| MetaCyc | 1.2.1.84 |
| UniProtKB/Swiss-Prot |
| Q39152, FACR1_ARATH; | Q5ZM72, FACR1_CHICK; | A1ZAI5, FACR1_DROME; |
| Q8WVX9, FACR1_HUMAN; | Q922J9, FACR1_MOUSE; | Q5R834, FACR1_PONAB; |
| Q66H50, FACR1_RAT; | Q7ZXF5, FACR1_XENLA; | Q08891, FACR2_ARATH; |
| Q0P5J1, FACR2_BOVIN; | A1ZAI3, FACR2_DROME; | Q96K12, FACR2_HUMAN; |
| Q7TNT2, FACR2_MOUSE; | Q93ZB9, FACR3_ARATH; | Q960W6, FACR3_DROME; |
| Q9LXN3, FACR4_ARATH; | Q0WRB0, FACR5_ARATH; | B9TSP7, FACR6_ARATH; |
| Q1PEI6, FACR8_ARATH; | Q9XGY7, FAR_SIMCH; |
|
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UniProtKB/Swiss-Prot entries corresponding to 1.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-