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ENZYME entry: EC 1.2.1.91

Accepted Name
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase.
Reaction catalysed
3-oxo-5,6-dehydrosuberyl-CoA semialdehyde + H2O + NADP(+) <=> 3-oxo-5,6-didehydrosuberyl-CoA + 2 H(+) + NADPH
Comment(s)
  • The enzyme from Escherichia coli is a bifunctional fusion protein that also catalyzes EC 3.3.2.12.
  • Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway.
  • Formerly EC 1.17.1.7.
Cross-references
BRENDA1.2.1.91
EC2PDB1.2.1.91
ExplorEnz1.2.1.91
PRIAM enzyme-specific profiles1.2.1.91
KEGG Ligand Database for Enzyme Nomenclature1.2.1.91
IUBMB Enzyme Nomenclature1.2.1.91
IntEnz1.2.1.91
MEDLINEFind literature relating to 1.2.1.91
MetaCyc1.2.1.91
Rhea expert-curated reactions1.2.1.91
UniProtKB/Swiss-Prot
P77455, PAAZ_ECOLI

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