A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.2.3.1
| Accepted Name |
|---|
| Aldehyde oxidase.
|
| Alternative Name(s) |
|---|
| Quinoline oxidase. |
| Retinal oxidase. |
| Reaction catalysed |
|---|
| An aldehyde + H(2)O + O(2) <=> a carboxylate + H(2)O(2) |
| Cofactor(s) |
|---|
| FAD; Iron-sulfur; Mo cation.
|
| Comment(s) |
|---|
- The enzyme from liver exhibits a broad substrate specificity, and is
involved in the metabolism of xenobiotics, including the oxidation of
N-heterocycles and aldehydes and the reduction of N-oxides,
nitrosamines, hydroxamic acids, azo dyes, nitropolycyclic aromatic
hydrocarbons, and sulfoxides.
- The enzyme is also responsible for the oxidation of retinal,
an activity that was initially attributed to a distinct enzyme
(EC 1.2.3.11).
- Formerly EC 1.2.3.11.
|
| Cross-references |
|---|
| PROSITE | PDOC00484 |
| BRENDA | 1.2.3.1 |
| EC2PDB | 1.2.3.1 |
| ExplorEnz | 1.2.3.1 |
| PRIAM enzyme-specific profiles | 1.2.3.1 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.2.3.1 |
| IUBMB Enzyme Nomenclature | 1.2.3.1 |
| IntEnz | 1.2.3.1 |
| MEDLINE | Find literature relating to 1.2.3.1 |
| MetaCyc | 1.2.3.1 |
| UniProtKB/Swiss-Prot |
| Q7XH05, ALDO1_ORYSJ; | Q852M1, ALDO2_ORYSJ; | Q852M2, ALDO3_ORYSJ; |
| Q69R21, ALDO4_ORYSJ; | P48034, AOXA_BOVIN; | H9TB17, AOXA_CAVPO; |
| Q06278, AOXA_HUMAN; | Q5FB27, AOXA_MACFA; | O54754, AOXA_MOUSE; |
| P80456, AOXA_RABIT; | Q9Z0U5, AOXA_RAT; | H9TB19, AOXB_CAVPO; |
| C4NYZ3, AOXB_MACFA; | Q5SGK3, AOXB_MOUSE; | Q5QE78, AOXB_RAT; |
| G3X982, AOXC_MOUSE; | Q5QE80, AOXC_RAT; | H9TB18, AOXD_CAVPO; |
| Q3TYQ9, AOXD_MOUSE; | Q5QE79, AOXD_RAT; | Q960A1, GAD3_CAEEL; |
| Q9FYG4, GLOX1_ARATH; | Q01772, GLOX_PHACH; | Q3HRQ2, GLOX_VITPS; |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot
entries referenced
in this entry, with possibility to download in different formats, align etc.
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.3.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-