ENZYME entry: EC 1.2.3.1
Accepted Name |
aldehyde oxidase.
|
Alternative Name(s) |
quinoline oxidase. |
retinal oxidase. |
Reaction catalysed |
an aldehyde + H2O + O2 <=> a carboxylate + H(+) + H2O2 |
Comment(s) |
- The enzyme from liver exhibits a broad substrate specificity, and is
involved in the metabolism of xenobiotics, including the oxidation of
N-heterocycles and aldehydes and the reduction of N-oxides,
nitrosamines, hydroxamic acids, azo dyes, nitropolycyclic aromatic
hydrocarbons, and sulfoxides.
- The enzyme is also responsible for the oxidation of retinal,
an activity that was initially attributed to a distinct enzyme
(EC 1.2.3.11).
- Formerly EC 1.2.3.11.
|
Cross-references |
BRENDA | 1.2.3.1 |
EC2PDB | 1.2.3.1 |
ExplorEnz | 1.2.3.1 |
PRIAM enzyme-specific profiles | 1.2.3.1 |
KEGG Ligand Database for Enzyme Nomenclature | 1.2.3.1 |
IUBMB Enzyme Nomenclature | 1.2.3.1 |
IntEnz | 1.2.3.1 |
MEDLINE | Find literature relating to 1.2.3.1 |
MetaCyc | 1.2.3.1 |
Rhea expert-curated reactions | 1.2.3.1 |
UniProtKB/Swiss-Prot |
Q7XH05, ALDO1_ORYSJ; | Q852M1, ALDO2_ORYSJ; | Q852M2, ALDO3_ORYSJ; |
Q7G191, ALDO4_ARATH; | Q69R21, ALDO4_ORYSJ; | P48034, AOXA_BOVIN; |
H9TB17, AOXA_CAVPO; | Q06278, AOXA_HUMAN; | Q5FB27, AOXA_MACFA; |
O54754, AOXA_MOUSE; | P80456, AOXA_RABIT; | Q9Z0U5, AOXA_RAT; |
H9TB19, AOXB_CAVPO; | C4NYZ3, AOXB_MACFA; | Q5SGK3, AOXB_MOUSE; |
Q5QE78, AOXB_RAT; | G3X982, AOXC_MOUSE; | Q5QE80, AOXC_RAT; |
H9TB18, AOXD_CAVPO; | Q3TYQ9, AOXD_MOUSE; | Q5QE79, AOXD_RAT; |
Q960A1, GAD3_CAEEL; | Q9FYG4, GLOX1_ARATH; | A0A2H4HHY6, GLOX_ARTAN; |
Q3HRQ2, GLOX_VITPS; |
|
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.2.3.-
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