ID   1.2.3.3
DE   pyruvate oxidase.
AN   phosphate-dependent pyruvate oxidase.
AN   pyruvic oxidase.
CA   H(+) + O2 + phosphate + pyruvate = acetyl phosphate + CO2 + H2O2.
CC   -!- Two reducing equivalents are transferred from the resonant
CC       carbanion/enamine forms of 2-hydroxyethyl-thiamine-diphosphate to the
CC       adjacent flavin cofactor, yielding 2-acetyl-thiamine diphosphate
CC       (AcThDP) and reduced flavin.
CC   -!- FADH is reoxidized by O2 to yield H2O2 and FAD and AcThDP is cleaved
CC       phosphorolytically to acetyl phosphate and thiamine diphosphate.
DR   P37063, POXB_LACPL ;  Q54970, POXB_STRPN ;
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