ID 1.2.5.1 DE pyruvate dehydrogenase (quinone). AN pyruvate dehydrogenase. AN pyruvate dehydrogenase (cytochrome). AN pyruvate oxidase. CA a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2. CC -!- This bacterial enzyme is located on the inner surface of the CC cytoplasmic membrane and coupled to the respiratory chain via CC ubiquinone. CC -!- Does not accept menaquinone. CC -!- Activity is greatly enhanced by lipids. CC -!- Requires thiamine diphosphate. CC -!- The enzyme can also form acetoin. DR P07003, POXB_ECOLI ; //