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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.2.99.6

Accepted Name
Carboxylate reductase.
Reaction catalysed
An aldehyde + acceptor + H(2)O <=> a carboxylate + reduced acceptor
Cofactor(s)
W cation.
Comment(s)
  • Methylviologen can act as acceptor.
  • In the reverse direction, non-activated acids are reduced by reduced viologens to aldehydes, but not to the corresponding alcohols.
Cross-references
BRENDA1.2.99.6
EC2PDB1.2.99.6
ExplorEnz1.2.99.6
PRIAM enzyme-specific profiles1.2.99.6
KEGG Ligand Database for Enzyme Nomenclature1.2.99.6
IUBMB Enzyme Nomenclature1.2.99.6
IntEnz1.2.99.6
MEDLINEFind literature relating to 1.2.99.6
MetaCyc1.2.99.6
UniProtKB/Swiss-Prot
Q8X6I9, PAOA_ECO57;  P77165, PAOA_ECOLI;  Q8X6J0, PAOB_ECO57;  
P77324, PAOB_ECOLI;  Q8X6J4, PAOC_ECO57;  P77489, PAOC_ECOLI;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.2.99.-
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