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ENZYME

ENZYME entry: EC 1.21.1.1

Accepted Name
iodotyrosine deiodinase
Alternative Name(s)
iodotyrosine dehalogenase 1
Reaction catalysed
2 iodide + L-tyrosine + 2 NADP(+) = 3,5-diiodo-L-tyrosine + H(+) + 2 NADPH
Comment(s)
  • The enzyme activity has only been demonstrated in the direction of 3-deiodination.
  • Formerly EC 1.22.1.1.
Cross-references
BRENDA1.21.1.1
EC2PDB1.21.1.1
ExplorEnz1.21.1.1
PRIAM enzyme-specific profiles1.21.1.1
KEGG Ligand Database for Enzyme Nomenclature1.21.1.1
IUBMB Enzyme Nomenclature1.21.1.1
IntEnz1.21.1.1
MEDLINEFind literature relating to 1.21.1.1
MetaCyc1.21.1.1
Rhea expert-curated reactions1.21.1.1
UniProtKB/Swiss-Prot
Q6PHW0, IYD1_HUMANQ9DCX8, IYD1_MOUSEQ6TA49, IYD1_PIG
Q5REW1, IYD1_PONABQ5BK17, IYD1_RATE7FDV5, IYD_DANRE
E9FR69, IYD_DAPPUE1JIB2, IYD_DROMEF4KU78, IYD_HALH1
T2MBC4, IYD_HYDVUA7S5D9, IYD_NEMVEB9K712, IYD_THENN

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.21.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-