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ENZYME

ENZYME entry: EC 1.21.3.10

Accepted Name
hercynylcysteine S-oxide synthase
Reaction catalysed
hercynine + L-cysteine + O2 <=> H2O + S-(hercyn-2-yl)-L-cysteine S-oxide
Comment(s)
  • Requires Fe(2+) for activity.
  • The enzyme, found in fungal species, is part of a fusion protein that also has the the activity of EC 2.1.1.44.
  • It is part of the biosynthesis pathway of ergothioneine.
  • The enzyme can also use L-selenocysteine to produce hercynylselenocysteine, which can be converted to selenoneine.
  • Formerly EC 1.14.99.51.
Cross-references
BRENDA1.21.3.10
EC2PDB1.21.3.10
ExplorEnz1.21.3.10
PRIAM enzyme-specific profiles1.21.3.10
KEGG Ligand Database for Enzyme Nomenclature1.21.3.10
IUBMB Enzyme Nomenclature1.21.3.10
IntEnz1.21.3.10
MEDLINEFind literature relating to 1.21.3.10
MetaCyc1.21.3.10
Rhea expert-curated reactions1.21.3.10
UniProtKB/Swiss-Prot
Q7RX33, EGT1_NEUCRO94632, EGT1_SCHPO

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