ID 1.21.98.2 DE dichlorochromopyrrolate synthase. CA 2 3-(7-chloroindol-3-yl)-2-iminopropanoate + H2O2 = CA dichlorochromopyrrolate + H(+) + 2 H2O + NH4(+). CC -!- This enzyme catalyzes a step in the biosynthesis of rebeccamycin, CC an indolocarbazole alkaloid produced by the bacterium Lechevalieria CC aerocolonigenes. CC -!- The enzyme is a dimeric heme-protein oxidase that catalyzes the CC oxidative dimerization of two L-tryptophan-derived molecules to form CC dichlorochromopyrrolic acid, the precursor for the fused six-ring CC indolocarbazole scaffold of rebeccamycin. CC -!- In vivo the enzyme uses hydrogen peroxide, formed by the enzyme CC upstream in the biosynthetic pathway (EC 1.4.3.23) as the electron CC acceptor. CC -!- However, the enzyme is also able to catalyze the reaction using CC molecular oxygen. CC -!- Formerly EC 1.21.3.9 and EC 4.3.1.26. DR Q8KHV6, REBD_LENAE ; //