ID 1.3.1.108 DE caffeoyl-CoA reductase. AN caffeoyl-CoA reductase-Etf complex. AN electron-bifurcating caffeoyl-CoA reductase. CA hydrocaffeoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (E)- CA caffeoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. CC -!- The enzyme, characterized from the bacterium Acetobacterium woodii, CC couples the endergonic ferredoxin reduction with NADH as reductant to CC the exergonic reduction of caffeoyl-CoA with the same reductant. CC -!- It uses the mechanism of electron bifurcation to overcome the steep CC energy barrier in ferredoxin reduction. CC -!- It also reduces 4-coumaroyl-CoA and feruloyl-CoA. DR H6LGM6, CARC_ACEWD ; H6LGM7, CARD_ACEWD ; H6LGM8, CARE_ACEWD ; //