ID   1.3.1.108
DE   Caffeoyl-CoA reductase.
AN   Caffeoyl-CoA reductase-Etf complex.
AN   Electron-bifurcating caffeoyl-CoA reductase.
CA   3-(3,4-dihydroxyphenyl)propanoyl-CoA + 2 NAD(+) + 2 reduced ferredoxin
CA   [iron-sulfur] cluster = (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl-CoA +
CA   2 NADH + 2 oxidized ferredoxin [iron-sulfur] cluster.
CF   FAD; Iron-sulfur.
CC   -!- The enzyme, characterized from the bacterium Acetobacterium woodii,
CC       couples the endergonic ferredoxin reduction with NADH as reductant to
CC       the exergonic reduction of caffeoyl-CoA with the same reductant.
CC   -!- It uses the mechanism of electron bifurcation to overcome the steep
CC       energy barrier in ferredoxin reduction.
CC   -!- It also reduces 4-coumaroyl-CoA and feruloyl-CoA.
DR   H6LGM6, CARC_ACEWD ;  H6LGM7, CARD_ACEWD ;  H6LGM8, CARE_ACEWD ;
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