ID 1.3.1.109 DE butanoyl-CoA dehydrogenase complex (NAD(+), ferredoxin). AN bifurcating butanoyl-CoA dehydrogenase. AN butanoyl-CoA dehydrogenase/Etf complex. CA butanoyl-CoA + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] = (2E)- CA butenoyl-CoA + 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin]. CC -!- The enzyme is a complex of a flavin-containing dehydrogenase CC component (Bcd) and an electron-transfer flavoprotein dimer (EtfAB). CC -!- The enzyme complex, isolated from the bacteria Acidaminococcus CC fermentans and butanoate-producing Clostridia species, couples the CC exergonic reduction of (E)-but-2-enoyl-CoA to butanoyl-CoA by NADH to CC the endergonic reduction of ferredoxin by NADH, using electron CC bifurcation to overcome the steep energy barrier in ferredoxin CC reduction. //