Expasy logo

ENZYME

ENZYME entry: EC 1.3.1.110

Accepted Name
lactate dehydrogenase (NAD(+),ferredoxin)
Alternative Name(s)
electron bifurcating LDH/Etf complex
Reaction catalysed
lactate + 2 NAD(+) + 2 reduced [2Fe-2S]-[ferredoxin] <=> 2 NADH + 2 oxidized [2Fe-2S]-[ferredoxin] + pyruvate
Comment(s)
The enzyme, isolated from the bacterium Acetobacterium woodii, uses flavin-based electron confurcation to drive endergonic lactate oxidation with NAD(+) as oxidant at the expense of simultaneous exergonic electron flow from reduced ferredoxin to NAD(+).
Cross-references
BRENDA1.3.1.110
EC2PDB1.3.1.110
ExplorEnz1.3.1.110
PRIAM enzyme-specific profiles1.3.1.110
KEGG Ligand Database for Enzyme Nomenclature1.3.1.110
IUBMB Enzyme Nomenclature1.3.1.110
IntEnz1.3.1.110
MEDLINEFind literature relating to 1.3.1.110
MetaCyc1.3.1.110
Rhea expert-curated reactions1.3.1.110
UniProtKB/Swiss-Prot
H6LBB0, LCTB_ACEWDH6LBB1, LCTC_ACEWDH6LBS1, LCTD_ACEWD

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-