ID 1.3.1.115 DE 3-oxocholoyl-CoA 4-desaturase. AN 3-oxo-choloyl-CoA dehydrogenase. CA (1) 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NAD(+) = CA 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA + H(+) + NADH. CA (2) 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NAD(+) = 7alpha-hydroxy-3- CA oxochol-4-en-24-oyl-CoA + H(+) + NADH. CC -!- The enzyme, characterized from the bacterium Clostridium scindens, CC participates in the bile acid 7alpha-dehydroxylation pathway. CC -!- The enzyme catalyzes the stereo-specific oxidation of its substrates CC and has no activity with the 7beta anomers. cf. EC 1.3.1.116. DR P19410, BAICD_CLOSV; //