ID   1.3.1.118
DE   meromycolic acid enoyl-[acyl-carrier-protein] reductase.
CA   a 2,3-saturated meromycolyl-[ACP] + NAD(+) = a trans-Delta(2)-
CA   meromycolyl-[ACP] + H(+) + NADH.
CC   -!- InhA is a component of the fatty acid synthase (FAS) II system of
CC       Mycobacterium tuberculosis, catalyzing an enoyl-[acyl-carrier-
CC       protein] reductase step.
CC   -!- The enzyme acts on very long and unsaturated fatty acids that form
CC       the meromycolic component of mycolic acids.
CC   -!- It extends FASI-derived C20 fatty acids to form C60 to C90 mycolic
CC       acids.
CC   -!- The enzyme, which forms a homotetramer, is the target of the
CC       preferred antitubercular drug isoniazid.
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