ID 1.3.1.118 DE meromycolic acid enoyl-[acyl-carrier-protein] reductase. CA a 2,3-saturated meromycolyl-[ACP] + NAD(+) = a trans-Delta(2)- CA meromycolyl-[ACP] + H(+) + NADH. CC -!- InhA is a component of the fatty acid synthase (FAS) II system of CC Mycobacterium tuberculosis, catalyzing an enoyl-[acyl-carrier- CC protein] reductase step. CC -!- The enzyme acts on very long and unsaturated fatty acids that form CC the meromycolic component of mycolic acids. CC -!- It extends FASI-derived C20 fatty acids to form C60 to C90 mycolic CC acids. CC -!- The enzyme, which forms a homotetramer, is the target of the CC preferred antitubercular drug isoniazid. //