ID   1.3.1.124
DE   2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing].
AN   Delta(2),Delta(4)-dienoyl-CoA reductase.
CA   (1) a (2E,4E)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(3E)-enoyl-CoA
CA   + NADP(+).
CA   (2) a (2E,4Z)-dienoyl-CoA + H(+) + NADPH = a 4,5-saturated-(3E)-enoyl-CoA
CA   + NADP(+).
CC   -!- This enzyme, characterized from eukaryotic organisms, catalyzes the
CC       reduction of either (2E,4E)-2,4-dienoyl-CoA or (2E,4Z)-2,4-dienoyl-
CC       CoA to (3E)-3-enoyl-CoA.
CC   -!- The best substrates for the enzyme from bovine liver have a chain-
CC       length of 8 or 10.
CC   -!- Mammals possess both mitochondrial and peroxisomal variants of this
CC       enzyme. cf. EC 1.3.1.34.
DR   Q23116, DEC12_CAEEL;  Q9LTV6, DECR2_ARATH;  Q6NV34, DECR2_DANRE;
DR   Q9NUI1, DECR2_HUMAN;  Q9WV68, DECR2_MOUSE;  Q5RBV3, DECR2_PONAB;
DR   Q9Z2M4, DECR2_RAT  ;  Q22230, DECR_CAEEL ;  Q16698, DECR_HUMAN ;
DR   Q9CQ62, DECR_MOUSE ;  Q64591, DECR_RAT   ;  P32573, SPS19_YEAST;
//