Expasy logo

ENZYME

ENZYME entry: EC 1.3.1.48

PURL: https://purl.expasy.org/enzyme/EC/1.3.1.48
Accepted Name
15-oxoprostaglandin 13-reductase
Alternative Name(s)
15-oxo-Delta(13)-prostaglandin reductase
prostaglandin 13-reductase
Reaction catalysed
  • 13,14-dihydro-15-oxo-prostaglandin E2 + NADP(+) = 15-oxoprostaglandin E2 + NADPH + H(+)
  • 13,14-dihydro-15-oxo-prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+)
Comment(s)
  • Reduces 15-oxoprostaglandins to 13,14-dihydro derivatives.
  • The enzyme from placenta is specific for NAD(+).
Cross-references
BRENDA1.3.1.48
EC2PDB1.3.1.48
ExplorEnz1.3.1.48
KEGG Ligand Database for Enzyme Nomenclature1.3.1.48
IUBMB Enzyme Nomenclature1.3.1.48
MEDLINEFind literature relating to 1.3.1.48
MetaCyc1.3.1.48
Rhea expert-curated reactions1.3.1.48
UniProtKB/Swiss-Prot
Q3SZJ4, PTGR1_BOVINQ9EQZ5, PTGR1_CAVPOQ14914, PTGR1_HUMAN
Q91YR9, PTGR1_MOUSEQ29073, PTGR1_PIGQ28719, PTGR1_RABIT
P97584, PTGR1_RATQ32L99, PTGR2_BOVINQ8N8N7, PTGR2_HUMAN
Q8VDQ1, PTGR2_MOUSEQ5R806, PTGR2_PONABQ5BK81, PTGR2_RAT
Q24K16, PTGR3_BOVINQ8N4Q0, PTGR3_HUMANQ8BGC4, PTGR3_MOUSE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-