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ENZYME entry: EC 1.3.1.72

Accepted Name
Delta(24)-sterol reductase.
Alternative Name(s)
Lanosterol Delta(24)-reductase.
Reaction catalysed
5-alpha-cholest-7-en-3-beta-ol + NADP(+) <=> 5-alpha-cholesta-7,24-dien-3-beta-ol + NADPH
Comment(s)
Acts on a range of steroids with a 24(25)-double bond, including lanosterol, desmosterol and zymosterol.
Cross-references
BRENDA1.3.1.72
EC2PDB1.3.1.72
ExplorEnz1.3.1.72
PRIAM enzyme-specific profiles1.3.1.72
KEGG Ligand Database for Enzyme Nomenclature1.3.1.72
IUBMB Enzyme Nomenclature1.3.1.72
IntEnz1.3.1.72
MEDLINEFind literature relating to 1.3.1.72
MetaCyc1.3.1.72
Rhea expert-curated reactions1.3.1.72
UniProtKB/Swiss-Prot
Q15392, DHC24_HUMAN;  Q60HC5, DHC24_MACFA;  Q8VCH6, DHC24_MOUSE;  
Q5BQE6, DHC24_RAT;  Q39085, DIM_ARATH;  P93472, DIM_PEA;  

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