ID 1.3.1.74 DE 2-alkenal reductase [NAD(P)(+)]. AN 2-alkenal reductase. AN NAD(P)H-dependent alkenal/one oxidoreductase. AN NADPH:2-alkenal alpha,beta-hydrogenase. CA (1) an n-alkanal + NAD(+) = an alk-2-enal + H(+) + NADH. CA (2) an n-alkanal + NADP(+) = an alk-2-enal + H(+) + NADPH. CC -!- Highly specific for 4-hydroxynon-2-enal and non-2-enal. CC -!- Alk-2-enals of shorter chain have lower affinities. CC -!- Exhibits high activities also for alk-2-enones such as but-3-en-2-one CC and pent-3-en-2-one. CC -!- Inactive with cyclohex-2-en-1-one and 12-oxophytodienoic acid. CC -!- Involved in the detoxification of alpha,beta-unsaturated aldehydes CC and ketones (cf. EC 1.3.1.102). DR Q39172, AER_ARATH ; Q39173, P2_ARATH ; Q3SZJ4, PTGR1_BOVIN; DR Q9EQZ5, PTGR1_CAVPO; Q14914, PTGR1_HUMAN; Q91YR9, PTGR1_MOUSE; DR Q29073, PTGR1_PIG ; Q28719, PTGR1_RABIT; P97584, PTGR1_RAT ; //