ID 1.3.1.77 DE Anthocyanidin reductase ((2R,3R)-flavan-3-ol-forming). AN ANR. AN Anthocyanidin reductase. CA A (2R,3R)-flavan-3-ol + 2 NAD(P)(+) = an anthocyanidin with a 3-hydroxy CA group + 2 NAD(P)H. CC -!- The enzyme participates in the flavonoid biosynthesis pathway found CC in plants. CC -!- It catalyzes the double reduction of anthocyanidins, producing CC (2R,3R)-flavan-3-ol monomers required for the formation of CC proanthocyanidins. CC -!- While the enzyme from the legume Medicago truncatula can use both CC NADPH and NADH as reductant, that from the crucifer Arabidopsis CC thaliana uses only NADPH. CC -!- Also, while the substrate preference of the M.truncatula is CC cyanidin>pelargonidin>delphinidin, the reverse preference is found CC with the Arabidopsis enzyme. CC -!- Cf. EC 1.3.1.112. DR Q9SEV0, BAN_ARATH ; //