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ENZYME entry: EC 1.3.1.8

Accepted Name
acyl-CoA dehydrogenase (NADP(+)).
Alternative Name(s)
2-enoyl-CoA reductase.
enoyl coenzyme A reductase.
Reaction catalysed
a 2,3-saturated acyl-CoA + NADP(+) <=> a 2,3-dehydroacyl-CoA + H(+) + NADPH
Comment(s)
  • The liver enzyme acts on enoyl-CoA derivatives of carbon chain length 4 to 16, with optimum activity on 2-hexenoyl-CoA.
  • In Escherichia coli, cis-specific and trans-specific enzymes exist (cf. EC 1.3.1.37 and EC 1.3.1.38).
Cross-references
BRENDA1.3.1.8
EC2PDB1.3.1.8
ExplorEnz1.3.1.8
PRIAM enzyme-specific profiles1.3.1.8
KEGG Ligand Database for Enzyme Nomenclature1.3.1.8
IUBMB Enzyme Nomenclature1.3.1.8
IntEnz1.3.1.8
MEDLINEFind literature relating to 1.3.1.8
MetaCyc1.3.1.8
Rhea expert-curated reactions1.3.1.8

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-