A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 1.3.1.85
| Accepted Name |
|---|
| Crotonyl-CoA carboxylase/reductase.
|
| Alternative Name(s) |
|---|
| CCR. |
| Crotonyl-CoA reductase (carboxylating). |
| Reaction catalysed |
|---|
| (2S)-ethylmalonyl-CoA + NADP(+) <=> (E)-but-2-enoyl-CoA + CO(2) + NADPH |
| Comment(s) |
|---|
- The reaction is catalyzed in the reverse direction.
- This enzyme, isolated from the bacterium Rhodobacter sphaeroides,
catalyzes (E)-but-2-enoyl-CoA-dependent oxidation of NADPH in the
presence of CO(2).
- When CO(2) is absent, the enzyme catalyzes the reduction of (E)-but-
2-enoyl-CoA to butanoyl-CoA, but with only 10% of maximal activity
(relative to (E)-but-2-enoyl-CoA carboxylation).
|
| Cross-references |
|---|
| BRENDA | 1.3.1.85 |
| EC2PDB | 1.3.1.85 |
| ExplorEnz | 1.3.1.85 |
| PRIAM enzyme-specific profiles | 1.3.1.85 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.3.1.85 |
| IUBMB Enzyme Nomenclature | 1.3.1.85 |
| IntEnz | 1.3.1.85 |
| MEDLINE | Find literature relating to 1.3.1.85 |
| MetaCyc | 1.3.1.85 |
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All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-