ID   1.3.1.88
DE   tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)].
AN   tRNA-dihydrouridine synthase 1.
CA   (1) 5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA +
CA   NADPH + H(+).
CA   (2) 5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH
CA   + H(+).
CA   (3) 5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA +
CA   NADPH + H(+).
CA   (4) 5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH
CA   + H(+).
CC   -!- The enzyme specifically modifies uracil(16) and uracil(17) in tRNA.
DR   Q6P1R4, DUS1L_HUMAN;  Q8C2P3, DUS1L_MOUSE;  Q8K582, DUS1L_RAT  ;
DR   Q9HGN6, DUS1_SCHPO ;  P53759, DUS1_YEAST ;
//