ID 1.3.1.94 DE polyprenol reductase. CA di-trans,poly-cis-dolichol + NADP(+) = di-trans,cis-polyprenol + H(+) + CA NADPH. CC -!- The reaction occurs in the reverse direction with reduction of the CC terminal double bond next to the alcohol group. CC -!- Isolated from human fetal brain tissue but present in all eukaryotes. CC -!- In mammalian cells dolichols are predominantly 18-21 isoprene units CC in length. DR P40526, DFG10_YEAST; Q9CAH5, POED1_ARATH; A2XWN6, POED1_ORYSI; DR Q7XUH5, POED1_ORYSJ; Q9SI62, POED2_ARATH; B8B6G5, POED2_ORYSI; DR Q7F0Q2, POED2_ORYSJ; D2HBV9, PORED_AILME; A8X8R3, PORED_CAEBR; DR Q17428, PORED_CAEEL; Q5RIU9, PORED_DANRE; Q9VLP9, PORED_DROME; DR Q9H8P0, PORED_HUMAN; C7T2J9, PORED_MESAU; Q9WUP4, PORED_MOUSE; DR Q5RJM1, PORED_RAT ; Q8AVI9, PORED_XENLA; Q0P4J9, PORED_XENTR; //