ID 1.3.1.n3 DE curcumin reductase. AN NADPH-dependent curcumin/dihydrocurcumin reductase. CA 2 NADP(+) + tetrahydrocurcumin = curcumin + 2 H(+) + 2 NADPH. CC -!- The enzyme, from the bacterium Escherichia coli is also active with CC 3-octene-2-one (59.7%), 3-hepten-2-one (28%), and resveratrol CC (14.8%). DR P76113, CURA_ECOLI ; //