ENZYME

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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 1.3.3.10

Accepted Name
Tryptophan alpha,beta-oxidase.
Alternative Name(s)
L-tryptophan 2',3'-oxidase.
L-tryptophan alpha,beta-dehydrogenase.
Reaction catalysed
L-tryptophan + O(2) <=> alpha,beta-didehydrotryptophan + H(2)O(2)
Cofactor(s)
Heme.
Comment(s)
The enzyme from Chromobacterium violaceum is specific for tryptophan derivatives possessing its carboxyl group free or as an amide or ester, and an unsubstituted indole ring. Also catalyzes the alpha,beta dehydrogenation of L-tryptophan side chains in peptides. The product of the reaction can hydrolyze spontaneously to form indolepyruvate. Formerly EC 1.4.3.17.
Cross-references
BRENDA	1.3.3.10
EC2PDB	1.3.3.10
ExplorEnz	1.3.3.10
PRIAM enzyme-specific profiles	1.3.3.10
KEGG Ligand Database for Enzyme Nomenclature	1.3.3.10
IUBMB Enzyme Nomenclature	1.3.3.10
IntEnz	1.3.3.10
MEDLINE	Find literature relating to 1.3.3.10
MetaCyc	1.3.3.10

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