ID   1.3.5.1
DE   succinate dehydrogenase.
AN   fumarate reductase (menaquinone).
AN   succinate dehydrogenase (menaquinone).
AN   succinate dehydrogenase (quinone).
AN   succinate dehydrogenase (ubiquinone).
AN   succinic dehydrogenase.
CA   a quinone + succinate = a quinol + fumarate.
CC   -!- A complex generally comprising an FAD-containing component that also
CC       binds the carboxylate substrate (A subunit), a component that
CC       contains three different iron-sulfur centers [2Fe-2S], [4Fe-4S],
CC       and [3Fe-4S] (B subunit), and a hydrophobic membrane-anchor component
CC       (C, or C and D subunits) that is also the site of the interaction
CC       with quinones.
CC   -!- The enzyme is found in the inner mitochondrial membrane in eukaryotes
CC       and the plasma membrane of bacteria and archaea, with the hydrophilic
CC       domain extending into the mitochondrial matrix and the cytoplasm,
CC       respectively.
CC   -!- Under aerobic conditions the enzyme catalyzes succinate oxidation,
CC       a key step in the citric acid (TCA) cycle, transferring the electrons
CC       to quinones in the membrane, thus linking the TCA cycle with the
CC       aerobic respiratory chain (where it is known as complex II).
CC   -!- Under anaerobic conditions the enzyme functions as a fumarate
CC       reductase, transferring electrons from the quinol pool to fumarate,
CC       and participating in anaerobic respiration with fumarate as the
CC       terminal electron acceptor.
CC   -!- The enzyme interacts with the quinone produced by the organism, such
CC       as ubiquinone, menaquinone, caldariellaquinone, thermoplasmaquinone,
CC       rhodoquinone etc. Some of the enzymes contain two heme subunits in
CC       their membrane anchor subunit.
CC   -!- These enzymes catalyze an electrogenic reaction and are thus
CC       classified as EC 7.1.1.12.
CC   -!- Formerly EC 1.3.5.4.
DR   Q9Z4P0, FRD2_SHEFN ;  P00363, FRDA_ECOLI ;  P44894, FRDA_HAEIN ;
DR   Q9ZMP0, FRDA_HELPJ ;  O06913, FRDA_HELPY ;  P64175, FRDA_MYCBO ;
DR   P9WN90, FRDA_MYCTO ;  P9WN91, FRDA_MYCTU ;  P20922, FRDA_PROVU ;
DR   V3TQ67, FRDA_SERS3 ;  Q07WU7, FRDA_SHEFN ;  P0C278, FRDA_SHEFR ;
DR   P83223, FRDA_SHEON ;  P17412, FRDA_WOLSU ;  P0AC49, FRDB_ECO57 ;
DR   P0AC48, FRDB_ECOL6 ;  P0AC47, FRDB_ECOLI ;  P44893, FRDB_HAEIN ;
DR   Q9ZMP1, FRDB_HELPJ ;  O06914, FRDB_HELPY ;  P9WN88, FRDB_MYCTO ;
DR   P9WN89, FRDB_MYCTU ;  P20921, FRDB_PROVU ;  P0AC50, FRDB_SHIFL ;
DR   P17596, FRDB_WOLSU ;  O82663, SDHA1_ARATH;  Q33862, SDHA1_ASCSU;
DR   Q9ZPX5, SDHA2_ARATH;  Q8WSR3, SDHA2_ASCSU;  Q6PA58, SDHAA_XENLA;
DR   Q801S2, SDHAB_XENLA;  P08065, SDHA_BACSU ;  P31039, SDHA_BOVIN ;
DR   Q09508, SDHA_CAEEL ;  Q9YHT1, SDHA_CHICK ;  P51054, SDHA_COXBU ;
DR   Q7ZVF3, SDHA_DANRE ;  Q9U3X4, SDHA_DICDI ;  Q94523, SDHA_DROME ;
DR   P0AC43, SDHA_ECO57 ;  P0AC42, SDHA_ECOL6 ;  P0AC41, SDHA_ECOLI ;
DR   P31040, SDHA_HUMAN ;  Q8HXW3, SDHA_MACFA ;  Q0QF17, SDHA_MESAU ;
DR   Q8K2B3, SDHA_MOUSE ;  Q6ZDY8, SDHA_ORYSJ ;  Q59661, SDHA_PARDE ;
DR   Q0QF01, SDHA_PIG   ;  Q5R616, SDHA_PONAB ;  Q920L2, SDHA_RAT   ;
DR   Q1RHB9, SDHA_RICBR ;  Q92J97, SDHA_RICCN ;  Q4UJM1, SDHA_RICFE ;
DR   P31038, SDHA_RICPR ;  Q68XN9, SDHA_RICTY ;  Q8ZQU3, SDHA_SALTY ;
DR   Q9UTJ7, SDHA_SCHPO ;  G4V4G6, SDHA_SERS3 ;  Q28ED0, SDHA_XENTR ;
DR   Q00711, SDHA_YEAST ;  Q8LBZ7, SDHB1_ARATH;  Q9S827, SDHB1_ORYSJ;
DR   Q8LB02, SDHB2_ARATH;  Q6H4G3, SDHB2_ORYSJ;  Q9FJP9, SDHB3_ARATH;
DR   O44074, SDHB_ASCSU ;  P08066, SDHB_BACSU ;  Q3T189, SDHB_BOVIN ;
DR   A8WPF0, SDHB_CAEBR ;  Q09545, SDHB_CAEEL ;  Q6FWS8, SDHB_CANGA ;
DR   Q9YHT2, SDHB_CHICK ;  P48932, SDHB_CHOCR ;  P51053, SDHB_COXBU ;
DR   P48933, SDHB_CYACA ;  A5PL98, SDHB_DANRE ;  Q55CC2, SDHB_DICDI ;
DR   P21914, SDHB_DROME ;  P07014, SDHB_ECOLI ;  Q75CI4, SDHB_EREGS ;
DR   P21912, SDHB_HUMAN ;  Q9CQA3, SDHB_MOUSE ;  Q59662, SDHB_PARDE ;
DR   Q007T0, SDHB_PIG   ;  P80477, SDHB_PORPU ;  P21913, SDHB_RAT   ;
DR   P80480, SDHB_RECAM ;  Q1RGP3, SDHB_RICBR ;  Q92JJ8, SDHB_RICCN ;
DR   Q4UN71, SDHB_RICFE ;  Q9ZEA1, SDHB_RICPR ;  Q68XS0, SDHB_RICTY ;
DR   Q8ZQU2, SDHB_SALTY ;  P21911, SDHB_SCHPO ;  Q70KF8, SDHB_UROFA ;
DR   P32420, SDHB_USTMA ;  Q3B8J8, SDHB_XENLA ;  B0BM36, SDHB_XENTR ;
DR   P21801, SDHB_YEAST ;  O42772, SDHB_ZYMTR ;  P47052, SDHX_YEAST ;
//