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ENZYME

ENZYME entry: EC 1.3.8.14

Accepted Name
L-prolyl-[peptidyl-carrier protein] dehydrogenase
Reaction catalysed
H(+) + L-prolyl-[peptidyl-carrier protein] + 2 oxidized [electron-transfer flavoprotein] = (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 reduced [electron-transfer flavoprotein]
Comment(s)
  • The enzyme participates in the biosynthesis of several pyrrole- containing compounds, such as undecylprodigiosin, prodigiosin, pyoluteorin, and coumermycin A1.
  • It is believed to catalyze the formation of a Delta(2)-pyrrolin-2- yl(carbonyl)-S-[peptidyl-carrier protein] intermediate, followed by a two-electron oxidation to 1H-pyrrol-2-carbonyl-[peptidyl-carrier protein].
Cross-references
BRENDA1.3.8.14
EC2PDB1.3.8.14
ExplorEnz1.3.8.14
PRIAM enzyme-specific profiles1.3.8.14
KEGG Ligand Database for Enzyme Nomenclature1.3.8.14
IUBMB Enzyme Nomenclature1.3.8.14
IntEnz1.3.8.14
MEDLINEFind literature relating to 1.3.8.14
MetaCyc1.3.8.14
Rhea expert-curated reactions1.3.8.14
UniProtKB/Swiss-Prot
Q5W271, PIGA_SERS3Q4KCY6, PLTE_PSEF5O54143, REDW_STRCO

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