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ENZYME entry: EC 1.3.8.15

Accepted Name
3-(aryl)acrylate reductase.
Reaction catalysed
  • H(+) + oxidized [electron-transfer flavoprotein] + phloretate <=> (E)-4-coumarate + reduced [electron-transfer flavoprotein]
  • 3-phenylpropanoate + H(+) + oxidized [electron-transfer flavoprotein] <=> (E)-cinnamate + reduced [electron-transfer flavoprotein]
  • 3-(1H-indol-3-yl)propanoate + H(+) + oxidized [electron-transfer flavoprotein] <=> (E)-3-(indol-3-yl)acrylate + reduced [electron-transfer flavoprotein]
Comment(s)
  • The enzyme, found in some amino acid-fermenting anaerobic bacteria, participates in the fermentation pathways of L-phenylalanine, L-tyrosine, and L-tryptophan.
  • Unlike EC 1.3.1.31, this enzyme has minimal activity with crotonate.
Cross-references
BRENDA1.3.8.15
EC2PDB1.3.8.15
ExplorEnz1.3.8.15
PRIAM enzyme-specific profiles1.3.8.15
KEGG Ligand Database for Enzyme Nomenclature1.3.8.15
IUBMB Enzyme Nomenclature1.3.8.15
IntEnz1.3.8.15
MEDLINEFind literature relating to 1.3.8.15
MetaCyc1.3.8.15
Rhea expert-curated reactions1.3.8.15
UniProtKB/Swiss-Prot
J7TF92, ACDA_CLOS1

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