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ENZYME

ENZYME entry: EC 1.3.8.2

PURL: https://purl.expasy.org/enzyme/EC/1.3.8.2
Accepted Name
4,4'-diapophytoene desaturase (4,4'-diapolycopene-forming)
Alternative Name(s)
4,4'-diapophytoene desaturase
dehydrosqualene desaturase
Reaction catalysed
15-cis-4,4'-diapophytoene + 4 FAD + 4 H(+) = all-trans-4,4'-diapolycopene + 4 FADH2
Comment(s)
  • The enzyme catalyzes four successive dehydrogenations, resulting in production of 4,4'-diapolycopene.
  • While the enzyme from Staphylococcus aureus was only shown to produce 4,4'-diaponeurosporene in vivo, it is able to catalyze the last reaction in vitro.
Cross-references
BRENDA1.3.8.2
EC2PDB1.3.8.2
ExplorEnz1.3.8.2
KEGG Ligand Database for Enzyme Nomenclature1.3.8.2
IUBMB Enzyme Nomenclature1.3.8.2
MEDLINEFind literature relating to 1.3.8.2
MetaCyc1.3.8.2
Rhea expert-curated reactions1.3.8.2
UniProtKB/Swiss-Prot
Q4VKV1, CRTN_METSP

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